The Duosoluble™ (both Hydrosoluble and Liposoluble) CoQ10, has been proven via several separate relative bioavailability studies in human subjects, to be a highly bioavailable CoQ10 oral supplement. A relative bioavailability study in dogs has confirmed these findings.

Additional studies have been carried out in rats to determine tissue uptake. Another bioavailability study carried out by an independent group has confirmed the superiority of Q-Gel Coenzyme Q10 over oil suspension softgels. In-vitro dissolution and cell-culture studies have also confirmed the absolute superiority of QGel Coenzyme Q10.

What is CoQ10?

Webster’s Ninth New Collegiate Dictionary defines coenzyme Q as ubiquinone (suggesting its widespread occurrence in nature) and describes it as "a quinone that functions as an electron transfer agent between cytochromes in the Krebs cycle."

Today, in a version known as coenzyme Q-10 (CoQ-10) or ubiquinol, this nutrient has become a popular seller and a product that is synonymous with increasing users’ cellular energy. Further, many studies have shown, it has value in combating various forms of cardiovascular disease, reducing the number and size of some tumors and treating gum disease. In fact, according to the newsletter Nutrition News, it has extended the life span of laboratory animals up to 56%. Yet, for almost 30 years, this powerful nutrient languished in the shadows, little understood and used by a scant few of the nutritional cognoscenti.

In the book All About Coenzyme Q-10, an entry in Avery Publishing Group’s series on Frequently Asked Questions (FAQ's), author Ray Sahelian, M.D., reports that CoQ-10’s discovery dates all the way to 1957. It was then that Frederick Crane, Ph.D., working at the University of Wisconsin, isolated an orange substance from the mitochondria of beef heart. The following year, says Sahelian, Karl Folkers, Ph.D., and coworkers at Merck synthesized the orange molecule in the laboratory. As one of the pioneering researchers, Folkers played a role in naming the substance CoQ-10. When he was in his 80s (he now is deceased), he mused about whether it would have sold better earlier had it been called a vitamin.

Technically speaking, however, CoQ-10 is not a vitamin. According to Sahelian, vitamins are nutrients that cannot be manufactured by the body, but must be ingested. CoQ-10 is manufactured by the body, but rarely in sufficient amounts to confer significant health benefits. Therefore, CoQ-10 is "vitamin-like" in that supplementation is needed.

In the mid 1970's, the Japanese perfected the industrial technology of fermentation to produce pure CoQ10 in significant quantities. To this day, virtually all CoQ10 still comes from Japan. There are two different methods of manufacture. One is via fermentation and the other is via a combination of fermentation and synthesis.

In the early 1970s, there were discoveries that people with gum disease and heart disease were deficient in CoQ-10. The momentum began to build and, by the early 1980's, CoQ-10 had reached a level of consumption in Japan that rivaled that country’s five top medications. In fact, all along, it has been the Japanese and the Europeans who have conducted the majority of clinical trials using CoQ-10.

Q-Gel® is a hydrosoluble CoQ10 supplement and the ONLY CoQ10 supplement that passes the dissolution test.

All of our Q-Gel® CoQ10 is produced via the fermentation process using a 100% natural yeast food source. All CoQ10 is obtained either by 100% fermentation using a special strain of yeast which yields NATURAL -- 100% ALL TRANS CoQ10 (the type we use in Q-Gel) -- or the cheaper synthetic alternative which involves partial fermentation and then synthesis using “solanesol” a chemical extracted from the tobacco leaf, (we do NOT use this type!). Please rest assured that there is no residual yeast in our Q-Gel products.

Q-Gel® CoQ10

Unlike most other forms of Coenzyme Q-10, our patented, hydrosoluble Q-Gel® CoQ10 passes the test for dissolution. Most other forms of CoQ10 exhibit dissolution levels of less than 1%. (Compare that to Q-Gel's® 100% dissolution!) Therefore, taking just one 30mg Q-Gel® CoQ10 softgel provides blood CoQ10 levels which are several times higher those achieved with other CoQ10 products. You can SAVE money and take less pills. Best of all, Q-Gel® CoQ10 delivers optimum levels of plasma CoQ-10 in just a few weeks or months NOT years as required with many other forms of CoQ10.

Q-Gel® has undergone clinical scrutiny in humans in several trials.

Q-Gel® is the preferred dosage form recommended by many physicians and cardiologists.

Q-Gel® is recommended by Jean Carper on page 40 in her runaway New York Times Bestseller, Miracle Cures.

Q-Gel® provides several fold higher CoQ10 plasma levels than conventional dosage forms and achieves therapeutic levels of CoQ10.

R. B. Singh, M.D., FACN, President, International College of Nutrition said: "Q-Gel Coenzyme Q10 softgels provide an immediate boost in blood CoQ10 levels and therapeutic levels exceeding 2.5 mcg/ml within weeks as revealed by research data."

Q-Gel® absorption is not dependent on the food you eat or proximity to meals and provides effective serum levels at lower dosages.

Q-Gel® is the only Coenzyme Q10 supplement formulated via the patented Bio-Solv® technology.

Is Q-Gel® CoQ10 a highly effective Coenzyme Q-10 product? YES! And clinical studies confirm Q-Gel's® absolute superiority over all dosage forms tested.

NEWS: Tishcon Corp. (the manufacturer of our Q-Gel CoQ10) has received an orphan drug designation for UbiQ-Gel® (CoQ-10) in the treatment of mitochondrial cytopathies. Phase 1 Clinical trials for UbiQ-Gel® have begun at the Children's Hospital Medical Center in Cincinnati, Ohio. UbiQ-Gel® is being clinically tested for use in the treatment of mitochondrial cytopathies a group of rare but debilitating diseases including MELAS syndrome, MERRF syndrome, and Kearnes-Sayre syndrome. All of which can cause heart disturbances, dementia, movement disorders, stroke-like episodes and seizures. All these diseases are thought to be caused by problems in the mitochondria, structures that produce energy in the body's cells. The heart contains the single largest concentration of CoQ10 in the body.